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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AQP9
All Species:
22.73
Human Site:
S222
Identified Species:
50
UniProt:
O43315
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43315
NP_066190.2
295
31401
S222
M
N
P
A
R
D
L
S
P
R
L
F
T
A
L
Chimpanzee
Pan troglodytes
XP_523087
295
31411
S222
M
N
P
A
R
D
L
S
P
R
L
F
T
A
L
Rhesus Macaque
Macaca mulatta
XP_001094912
295
31511
S222
M
N
P
A
R
D
L
S
P
R
L
F
T
A
L
Dog
Lupus familis
XP_544701
295
31519
S222
M
N
P
A
R
D
L
S
P
R
L
F
T
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJJ3
295
31746
S222
M
N
P
A
R
D
L
S
P
R
L
F
T
A
L
Rat
Rattus norvegicus
P56627
295
31852
S222
M
N
P
A
R
D
L
S
P
R
L
F
T
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512694
292
31482
G221
V
N
P
A
R
D
F
G
P
R
L
F
T
A
I
Chicken
Gallus gallus
XP_001233182
287
30764
G219
M
N
P
A
R
D
L
G
P
R
L
F
T
A
I
Frog
Xenopus laevis
NP_001081876
292
31681
G221
V
N
P
A
R
D
F
G
P
R
L
F
T
S
L
Zebra Danio
Brachydanio rerio
NP_001028268
294
31573
G211
L
N
P
A
R
D
L
G
P
R
L
F
T
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FIZ9
283
30198
G220
M
N
P
A
R
S
L
G
P
A
L
V
M
G
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.9
90.5
N.A.
75.9
75.9
N.A.
45.4
63.3
46.4
53.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
97.6
93.5
N.A.
84.4
85.7
N.A.
62
78.9
63.3
70.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
73.3
86.6
73.3
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
93.3
86.6
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
100
0
0
0
0
0
10
0
0
0
82
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
91
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
19
0
0
0
0
91
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
46
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
0
0
0
82
0
0
0
100
0
0
0
73
% L
% Met:
73
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
100
0
0
0
0
0
100
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
100
0
0
0
0
91
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
10
0
55
0
0
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
91
0
0
% T
% Val:
19
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _